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Research Page

My main scientific interests are retinal physiology and optics. Retinal physiology dates back to my PhD project in physics at the Department of Biophysics, University of Groningen, and the Department of Zoology, University of Cambridge. At that time (1989-1993) I studied photoreceptor metabolism (sodium and potassium homeostasis and oxygen consumption) and spatiotemporal properties of ganglion cells in insects. Optics dates back to my postdoc project (1994-1995) in physiological optics at the Laboratory of Experimental Ophthalmology, University of Groningen.

Currently, the research I'm involved in deals with physiological optics, epidemiology and perimetry. Optics includes psychophysics, contrast sensitivity related issues and theoretical work; epidemiology and perimetry are mainly directed towards glaucoma, my current subspecialty as an ophthalmologist. The central theme of the optical research is the interaction between the aberrations of the human eye and the processing of visual information. The final aim of the glaucoma research is to improve glaucoma care by contributing to the development of evidence-based, protocolised and tailor-made testing strategies for the detection and monitoring of glaucoma: what test should be performed when in which person and what should be done with the test result. Most data used in this branch are collected in the "Groningen Longitudinal Glaucoma Study", a longitudinal observational study with almost 1000 participants, begun in 2000. Optics and glaucoma converge into the central theme of early processing in the visual system: how are objects imaged on the retina and how are the images processed.

latest update: 31-1-2012

Some pictures from my PhD project: intracellular recording from Calliphora vicina photoreceptor, optic chiasm of Calliphora vicina, and spikes recorded from optic chiasm (presumably from L4 and L5).